Have you tried Adaware?  I run it at least once 
a week and since I've been on the forum it's 
been picking up about eleven to fourteen more 
spyware programs every time I run it.  It 
disables the spyware, though.  I've been getting 
less spam since I've been using it too!

You can download it from Cnet or 
www.lavasoft.com.