You mentioned "hand inked" in your post, but I 
just want to clarify the differences between hand-
inked and hand-painted.

Hand inking is when the animator-artist-dude 
actually uses a pen and ink and draws in all the 
lines on the acetate for animation. This is the 
way all older disney cels were made (one of the 
reason's that they are so expensive). Majority of 
anime cels' lines were xeroxed off of a special 
machine, onto the acetate. This was cheaper and 
faster. This is also why the lines fade on 
xeroxed-line cels, and not really on hand-inked 
cels.

Hand-painted means that a worker at the studio 
actually physically painted all of the parts 
(colors - not the outlines) of the cel with a 
paint brush (not a machine). 

As for your question about reproduction cels, I 
used to own one, and I know for a fact that the 
studio pierrot one you are tempted to purchase is 
a very well done high quality reproduction. It 
looks just like a production cel, except more 
carefully painted, and solid copy lines.

hope that helps. ^_^